日本高清视频在线www色-黄又色又污又爽又高潮动态图-国产精品无码av无码-亚洲色欲色欲www在线丝-日本无遮挡真人祼交视频

當(dāng)前位置:網(wǎng)站首頁產(chǎn)品展示抗體單克隆抗體 > YP-Ab-00077MTDH Monoclonal Antibody
MTDH Monoclonal Antibody

MTDH Monoclonal Antibody

簡要描述:MTDH Monoclonal Antibody
宿主: Monoclonal, Mouse
反應(yīng)性: Human
應(yīng)用: WB;IHC;IF;FCM;ELISA

產(chǎn)品型號: YP-Ab-00077

所屬分類:單克隆抗體

更新時間:2024-11-01

詳細(xì)說明:

MTDH Monoclonal Antibody

抗體,也叫免疫球蛋白(Ig),是一種能特異性結(jié)合抗原的糖蛋白,而抗原是在易感染動物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi),抗體是由于外源性分子的侵襲而產(chǎn)生的。抗體以一個或者多個Y字形單體存在,每個Y字形單體由4條多肽鏈組成,包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈?zhǔn)歉鶕?jù)它們的分子量大小來命名的。Y字形結(jié)構(gòu)的頂端是可變區(qū),為抗原結(jié)合部位。任何一個抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結(jié)構(gòu)上的差異),每一個抗體的重鏈則決定了它的類或型。

產(chǎn)品詳情
MTDH Monoclonal Antibody detects endogenous levels of MTDH protein.
免疫原詳細(xì)信息
Purified recombinant fragment of human MTDH expressed in E. Coli.
相關(guān)試劑
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
背景
caution:Was originally (PubMed:15093543) thought to be a type II membrane protein but this is inconsistent with the results of multiple phosphorylation studies because this topology would locate the phosphorylation sites in the lumen or extracellularly rather than in the cytoplasm.,function:Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.,induction:By TNF-alpha (at protein level). By HIV-1 infection of primary fetal astrocytes.,miscellaneous:Knockdown significantly reduces the adhesion of cancer cells to lung microvascular endothelial cells and the reciprocal effect is observed following overexpression.,subcellular location:In epithelial cells, recruited to tight junctions (TJ) during the maturation of the TJ complexes. A nucleolar staining may be due to nuclear targeting of an isoform lacking the transmembrane domain (By similarity). TNF-alpha causes translocation from the cytoplasm to the nucleus.,subunit:Interacts with BCIPP, CREBBP/CBP and RELA/p65.,tissue specificity:Widely expressed with highest levels in muscle-dominating organs such as skeletal muscle, heart, tongue and small intestine and in endocrine glands such as thyroid and adrenal gland. Overexpressed in various cancers including breast, brain, prostate, melanoma and glioblastoma multiforme

天津俊達(dá)生物科技有限公司,是從事實(shí)驗室耗材銷售的現(xiàn)代化生物科技企業(yè),公司本著“誠信為本,互利共贏"的核心價值觀,秉承“以市場為導(dǎo)向,提供服務(wù)"的宗旨為各大院校、科研單位、第三方實(shí)驗室檢測機(jī)構(gòu)等提供的產(chǎn)品和服務(wù)。目前公司主要經(jīng)營分子生物學(xué)、細(xì)胞生物學(xué)、免疫學(xué)等生物學(xué)產(chǎn)品,多種實(shí)驗室耗材 歡迎垂詢!


備注:圖片僅供參考。僅供科研,不可用于臨床。




留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說明:

  • 驗證碼:

    請輸入計算結(jié)果(填寫阿拉伯?dāng)?shù)字),如:三加四=7

主站蜘蛛池模板: 美女露出奶头扒开尿口免费网站| 精品亚洲欧美自拍| 亚洲男人的天堂www| 大又大粗又爽又黄少妇毛片 | 麻花传媒在线mv免费观看视频| 天天干天天日夜夜操| 欧美丰满大爆乳波霸奶水多| 欧洲成人一区二区三区| 国产在线观看超清无码视频一区二区 | 久久久婷婷五月亚洲97号色| 免费人成自慰网站| 成人无号精品一区二区三区| 无遮挡啪啪摇乳动态图gif| 熟妇女人妻丰满少妇中文字幕| 992tv精品视频tv在线观看| 少妇高潮a视频| 成人超碰| 免费做a爰片久久毛片a片下载| 国产成+人+综合+欧美亚洲| 亚洲国产精品自产在线播放 | 小sao货水好多真紧h视频| 国产成人vr精品a视频| 性男女做视频观看网站| 俄罗斯老熟妇色xxxx| 精品久久久久久777米琪桃花| 又色又污又爽又黄的网站| 日韩a无v码在线播放| 欧美特黄特色三级视频在线观看| 久久99精品久久久久久hb| 国产精品乱码高清在线观看 | 在线看亚洲十八禁网站| 无码免费的毛片基地| 97人人澡| 亚洲人成图片小说网站| 伊人久久大香线蕉亚洲| 日本大肚子孕妇交xxx| 亚洲va无码va在线va天堂| 亚洲国产欧美在线人成aaaa| 国产精品视频一区二区亚瑟| 国产精品无码久久四虎| 久久九九有精品国产尤物|